Milan Jirsa Selected Research

Hereditary Hyperbilirubinemia (Rotor Syndrome)

10/2015	Radionuclide cholescintigraphy in genetically confirmed Rotor syndrome.
10/2013	New insights in bilirubin metabolism and their clinical implications.
2/2012	Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

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Milan Jirsa Research Topics

Disease

7	Liver Diseases (Liver Disease) 05/2020 - 04/2008
6	Hyperbilirubinemia 01/2019 - 02/2002
6	Jaundice (Icterus) 01/2018 - 09/2004
5	Fibrosis (Cirrhosis) 03/2020 - 01/2016
4	Hepatolenticular Degeneration (Wilson's Disease) 03/2020 - 01/2007
4	Cholestasis 03/2020 - 01/2015
4	Neoplasms (Cancer) 01/2019 - 04/2008
4	Intrahepatic Cholestasis 01/2019 - 09/2004
4	Gilbert Disease 10/2015 - 02/2002
3	Cholelithiasis 03/2020 - 01/2003
3	progressive familial intrahepatic 1 Cholestasis 03/2020 - 09/2009
3	Hereditary Hyperbilirubinemia (Rotor Syndrome) 10/2015 - 02/2012
3	Chronic Idiopathic Jaundice (Dubin Johnson Syndrome) 02/2013 - 07/2005
2	Proteinuria 01/2022 - 02/2002
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 01/2015
2	Ornithine Carbamoyltransferase Deficiency Disease 06/2018 - 04/2010
2	Necrosis 03/2018 - 01/2017
2	Pruritus (Itching) 01/2018 - 10/2014
2	Iron Overload 01/2017 - 12/2016
2	Gallstones (Gallstone) 05/2014 - 01/2003
2	End Stage Liver Disease 04/2014 - 01/2007
1	Inflammation (Inflammations) 01/2022
1	Chronic Renal Insufficiency 01/2022
1	Intrahepatic Cholestasis of Pregnancy 03/2020
1	Cystitis 01/2019
1	Liver Neoplasms (Liver Cancer) 01/2019
1	Hyperammonemia 06/2018
1	Diabetes Mellitus 05/2018
1	Hepatocellular Carcinoma (Hepatoma) 11/2017
1	Chronic Pancreatitis 01/2017
1	Atrophy 01/2017
1	Pancreatitis 01/2017
1	Anemia 12/2016
1	Hemochromatosis (Bronze Diabetes) 12/2016
1	Cardiomyopathies (Cardiomyopathy) 12/2016
1	Muscular Diseases (Myopathy) 01/2016
1	Type 2 Diabetes Mellitus (MODY) 01/2016
1	Autoimmune Diseases (Autoimmune Disease) 10/2015
1	Chemical and Drug Induced Liver Injury 10/2015
1	Hemolytic Anemia 10/2015
1	Chronic Kidney Failure (Chronic Renal Failure) 05/2015
1	Chronic Hepatitis C 01/2015

Drug/Important Bio-Agent (IBA)

7	BilirubinIBA 01/2015 - 02/2002
4	Proteins (Proteins, Gene)FDA Link 03/2020 - 04/2008
4	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 01/2019 - 09/2004
4	CholesterolIBA 05/2014 - 01/2003
3	Phospholipids (Phosphatides)FDA LinkGeneric 03/2020 - 05/2014
3	Triglycerides (Triacylglycerol)IBA 01/2020 - 01/2016
2	Adenosine Triphosphate (ATP)IBA 03/2020 - 06/2003
2	Pharmaceutical PreparationsIBA 03/2020 - 01/2018
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2018 - 01/2017
2	IronIBA 01/2017 - 12/2016
2	Ribavirin (Virazole)FDA LinkGeneric 05/2015 - 01/2015
2	InterferonsIBA 05/2015 - 01/2015
2	Multidrug Resistance-Associated Protein 2IBA 02/2013 - 05/2007
2	Member 11 Subfamily B ATP Binding Cassette TransporterIBA 09/2009 - 04/2008
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2009 - 01/2002
1	Protein Isoforms (Isoforms)IBA 01/2022
1	AA amyloidosisIBA 01/2022
1	Serum Amyloid A Protein (Serum Amyloid A)IBA 01/2022
1	Amyloid (Amyloid Fibrils)IBA 01/2022
1	OsteopontinIBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Contrast MediaIBA 05/2020
1	TransferasesIBA 03/2020
1	CopperIBA 03/2020
1	Membrane LipidsIBA 03/2020
1	TOR Serine-Threonine KinasesIBA 01/2019
1	Plasma GasesIBA 01/2019
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2019
1	Cantharidin (Cantharides)IBA 01/2019
1	Cefprozil (Cefzil)FDA LinkGeneric 01/2019
1	Nonsense Codon (Nonsense Mutation)IBA 01/2019
1	Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA 06/2018
1	Ornithine Carbamoyltransferase (Ornithine Transcarbamylase)IBA 06/2018
1	Cyclophilins (Cyclophilin)IBA 03/2018
1	LipidsIBA 01/2018
1	Bile Acids and Salts (Bile Acids)IBA 01/2018
1	Polystyrenes (Polystyrene)IBA 11/2017
1	Silicon Dioxide (Silica)FDA LinkGeneric 11/2017
1	Hydroxyl RadicalIBA 11/2017
1	HeliumIBA 01/2017
1	OzoneIBA 01/2017
1	HepcidinsIBA 01/2017
1	DeferiproneIBA 12/2016
1	Chelating AgentsIBA 12/2016
1	Deferoxamine (Desferal)FDA LinkGeneric 12/2016
1	CreatinineIBA 01/2016
1	Mycophenolic Acid (Cellcept)FDA LinkGeneric 01/2016
1	Alkaline PhosphataseIBA 01/2016
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2016
1	TrypsinIBA 10/2015
1	Radioisotopes (Radionuclides)IBA 10/2015
1	ParaffinIBA 01/2015
1	Interferon-alpha (Interferon Alfa)IBA 01/2015
1	Formaldehyde (Formol)FDA Link 01/2015

Therapy/Procedure

7	Liver Transplantation 01/2021 - 01/2007
5	Therapeutics 01/2019 - 01/2009
1	Parenteral Nutrition 03/2020
1	Lasers (Laser) 03/2018